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@media(min-width:1600px){.library-hero,.library-tools,.library-endnote{max-width:1465px;margin-left:auto;margin-right:auto}.site-header,.site-footer{padding-left:max(4.2%,calc((100vw - 1465px)/2));padding-right:max(4.2%,calc((100vw - 1465px)/2))}}
@media(max-width:1150px){.library-toolbar{align-items:flex-start;flex-direction:column;gap:20px}.search-box{width:100%;max-width:400px}.category-filters{gap:24px}.library-hero{gap:30px;padding-top:50px}.hero-copy h1{font-size:54px}.detail-layout{grid-template-columns:200px minmax(0,1fr);gap:35px}.protocol-tabs{gap:18px}.protocol-tab{font-size:9px}.header-context{display:none}.edition-label{padding-left:20px}.list-head,.protocol-row{grid-template-columns:100px minmax(0,1fr) 135px 24px;gap:18px}}
@media(max-width:800px){.site-header{gap:18px;padding:16px 5%;min-height:78px}.brand-mark{width:36px;height:36px}.brand-name{font-size:11px}.brand-name span{font-size:7px}.edition-label{display:none}.header-library{font-size:11px}.library-hero{grid-template-columns:1fr;margin:0 5%;padding:42px 0 35px;gap:0}.hero-copy h1{font-size:clamp(38px,7vw,56px)}.hero-description{font-size:14px;max-width:560px}.atlas-art{display:none}.eyebrow{font-size:8px;letter-spacing:.1em}.hero-meta{font-size:8px;gap:9px;flex-wrap:wrap}.library-tools{margin:0 5%;padding-top:28px}.category-filters{gap:18px;row-gap:3px}.category-filter{font-size:11px}.search-box{max-width:none}.results-meta{margin-top:26px}.results-meta>span{display:none}.list-head,.protocol-row{grid-template-columns:75px minmax(0,1fr) 24px;gap:13px;padding-left:0;padding-right:0}.list-head>span:nth-child(3){display:none}.protocol-row{position:relative;padding-top:20px;padding-bottom:20px;align-items:start}.row-body h2{font-size:23px;line-height:1.2}.row-body p{font-size:11px;-webkit-line-clamp:2}.row-ref{padding-top:3px}.row-category{font-size:8px}.row-status{grid-column:2;grid-row:2}.row-arrow{grid-column:3;grid-row:1;line-height:1;padding-top:3px}.status{font-size:9px}.library-endnote{margin:0 5%;padding:26px 0;gap:12px}.endnote-index{display:none}.library-endnote p{font-size:10px}.detail-layout{display:block;padding:25px 5% 45px}.detail-sidebar{position:static;margin-bottom:30px}.back-link{margin-bottom:16px}.mobile-index-toggle{display:flex;width:100%;align-items:center;justify-content:space-between;border:1px solid var(--line);padding:10px 12px;background:none;font-size:11px}.mobile-index-toggle span{font-size:16px;color:var(--oxide)}.sidebar-index{display:none;border:1px solid var(--line);border-top:0;padding:17px 14px}.sidebar-index.open{display:block}.sidebar-category{font-size:23px;margin-bottom:12px}.sidebar-eyebrow{display:none}.sidebar-note{font-size:9px;margin-top:15px}.sidebar-list{max-height:270px;overflow:auto}.sidebar-link{font-size:10px;padding:10px 0}.protocol-heading h1{font-size:43px}.protocol-summary{font-size:14px;line-height:1.75}.protocol-kicker{align-items:flex-start;margin-bottom:20px}.protocol-kicker .eyebrow{font-size:8px;max-width:70%}.protocol-kicker .status{font-size:8px}.protocol-actions{gap:20px}.protocol-tabs{gap:21px;padding-top:8px}.protocol-tab{font-size:10px}.tabs-wrap{margin-bottom:27px}.content-section h2,.panel-heading{font-size:27px}.content-section p,.prose-text{font-size:13px;line-height:1.85}.numbered-steps li,.plain-list li{font-size:12px}.overview-definition{font-size:23px}.overview-section-list{grid-template-columns:1fr}.spec-row{grid-template-columns:30% minmax(0,1fr);gap:20px;padding:16px 0}.spec-row dt{font-size:10px}.spec-row dd{font-size:12px}.evidence-link{font-size:21px}.site-footer{padding:25px 5%;align-items:flex-start}.site-footer>div{flex-direction:column;gap:4px;align-items:flex-start}.site-footer>div:last-child{align-items:flex-end;text-align:right}.footer-brand{font-size:8px}.error-state{padding:55px 5%}.case-facts{gap:15px 25px}}
@media(max-width:420px){.hero-copy h1{font-size:38px}.protocol-heading h1{font-size:36px}.protocol-kicker{flex-wrap:wrap;gap:12px}.protocol-kicker .eyebrow{max-width:100%}.list-head,.protocol-row{grid-template-columns:60px minmax(0,1fr) 18px;gap:10px}.row-body h2{font-size:21px}.category-filters{gap:15px}.category-filter{font-size:10px}.brand{gap:9px}.header-library span{margin-left:8px}.protocol-review-note{font-size:9px}.spec-row{grid-template-columns:1fr;gap:5px}}
@media(max-width:800px){.row-ref .row-category{display:block}.row-status{display:none}.procedure-figures{grid-template-columns:1fr;gap:24px;margin-bottom:28px}.figure-dialog{padding:38px 16px 20px}.procedure-figure img{padding:12px;max-height:330px}}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*{transition:none!important}}
@media print{.figure-dialog{display:none!important}.procedure-figures{display:block;border:0;padding:0;max-width:none}.procedure-figure{break-inside:avoid;margin-bottom:20pt}.procedure-figure img{max-height:100mm;width:auto;max-width:100%;padding:0;margin:0 auto}.figure-caption{font-size:9pt}.figure-credit{font-size:8pt}.product-match-note{break-inside:avoid}}
@media print{@page{size:letter;margin:18mm}html{scroll-behavior:auto}body{background:white;color:#172a20;font-size:10pt}.site-header,.site-footer,.skip-link,.detail-sidebar,.detail-article,.library-hero,.library-tools,.library-endnote,.error-state,.loading-state{display:none!important}#detail-view{display:block!important;padding:0;margin:0;max-width:none}.print-sheet{display:block!important}.print-brand{font:9pt var(--sans);letter-spacing:.12em;border-bottom:1pt solid #173c31;padding-bottom:10pt;margin-bottom:20pt}.print-sheet h1{font:28pt/1.15 var(--serif);letter-spacing:-.025em;color:#173c31;margin:0 0 12pt}.print-status{font:9pt var(--sans);color:#a04a32;margin:0 0 12pt}.print-summary{font:11pt/1.6 var(--sans);margin-bottom:20pt}.print-section{margin:18pt 0 24pt}.print-section>h2{font:19pt var(--serif);border-top:.6pt solid #c1c9bd;padding-top:12pt;color:#173c31;margin-bottom:14pt;break-after:avoid}.content-section{margin-bottom:20pt;max-width:none}.content-section h2{font-size:15pt}.content-section p,.prose-text{font-size:10pt;line-height:1.6;max-width:none}.numbered-steps li,.plain-list li{font-size:9.5pt;line-height:1.6;break-inside:avoid}.numbered-steps li{padding-top:10pt;padding-bottom:10pt}.numbered-steps li::before{top:12pt}.plain-list li{padding-top:7pt;padding-bottom:7pt}.plain-list li::before{top:15pt}.spec-row{break-inside:avoid;padding:12pt 0}.spec-row dt,.spec-row dd{font-size:9.5pt}.evidence-item{break-inside:avoid}.evidence-link{font-size:13pt}.evidence-item p,.case-study p{font-size:9.5pt}.clinical-note{padding:12pt 15pt;break-inside:avoid;background:#f1f2eb;print-color-adjust:exact}.clinical-note p{font-size:9pt}.overview-definition{font-size:14pt}.case-study h2{font-size:16pt}.case-facts{break-inside:avoid}.case-facts dt{font-size:8pt}.case-facts dd{font-size:9pt}.print-sheet a{text-decoration:none;overflow-wrap:anywhere}.print-sheet .evidence-link[href]::after{content:" (" attr(href) ")";display:block;font:8pt/1.5 var(--sans);margin-top:5pt;color:#5c675d}.external-arrow{display:none}.print-footnote{margin-top:25pt;padding-top:10pt;border-top:.6pt solid #c1c9bd;font:8pt/1.6 var(--sans);color:#5b675d}#library-view{display:none!important}}

.source-specs{background:#f7edcf;border-top-color:#b69a57}.source-specs .spec-row{padding-left:15px;padding-right:15px;border-color:#dfcf9f}.source-handling{background:#f7edcf;padding:0 18px!important;max-width:860px}.source-handling li{border-color:#dfcf9f!important}.handling-source-note{font-size:12px;color:#715c29;line-height:1.7;max-width:76ch}@media print{.source-specs,.source-handling{print-color-adjust:exact;-webkit-print-color-adjust:exact}}

@media print{#detail-view[hidden]{display:none!important}}

.imaging-requirement{max-width:860px;margin:0 0 24px;padding:16px 20px;border:1px solid #9aa991;border-left:4px solid var(--ink);background:#e7ecdf;color:var(--ink);overflow-wrap:anywhere}.imaging-requirement-label{display:block;font-size:13px;line-height:1.5;font-weight:700}.imaging-requirement-detail{font-size:12px;line-height:1.75;color:#324b3c;margin:6px 0 0;max-width:78ch}.imaging-requirement-compact{padding:11px 15px;margin-bottom:20px}.imaging-requirement-compact .imaging-requirement-label{font-size:12px}.procedure-figures-link{max-width:860px;display:flex;align-items:center;gap:14px;padding:13px 0;margin:0 0 28px;border-bottom:1px solid var(--line);font-size:12px;line-height:1.5;color:var(--ink)}.procedure-figures-link:hover{border-color:var(--oxide);color:var(--oxide)}.figure-link-count{font-size:10px;color:var(--muted);white-space:nowrap}.figure-link-arrow{margin-left:auto;font-size:18px;flex-shrink:0}.figure-kind{display:inline-block;margin:12px 0 0;padding:3px 8px;border:1px solid #aab7a2;background:#e7ecdf;color:#234634;font-size:9px;line-height:1.5;font-weight:650;letter-spacing:.025em}.figure-kind-conceptual{background:#f3e8d3;border-color:#c2a979;color:#614b24}.figure-kind+.figure-caption{margin-top:8px}
@media(max-width:800px){.imaging-requirement{padding:14px 16px;margin-bottom:22px}.imaging-requirement-label{font-size:12px}.imaging-requirement-detail{font-size:11px}.imaging-requirement-compact{padding:10px 13px;margin-bottom:18px}.procedure-figures-link{flex-wrap:wrap;gap:6px 12px;font-size:11px;margin-bottom:24px}.figure-link-count{font-size:9px}.figure-link-arrow{margin-left:auto}.figure-kind{font-size:9px}}
@media print{.imaging-requirement{margin:0 0 16pt;padding:10pt 12pt;border-color:#8a9a80;border-left:2pt solid #173c31;background:#e7ecdf;color:#173c31;break-inside:avoid;print-color-adjust:exact;-webkit-print-color-adjust:exact}.imaging-requirement-label{font-size:10pt}.imaging-requirement-detail{font-size:9pt;line-height:1.6;margin-top:4pt;color:#324b3c}.figure-kind{font-size:8pt;print-color-adjust:exact;-webkit-print-color-adjust:exact}.figure-enlarge-label,.procedure-figures-link{display:none!important}}

.eligibility-checklist { margin: 2.3rem 0; padding-top: 1.4rem; border-top: 1px solid var(--rule, #c9ccc0); }
.eligibility-checklist h2 { font-family: var(--sans, Arial, sans-serif); font-size: .78rem; line-height: 1.6; letter-spacing: .09em; text-transform: uppercase; margin-bottom: 1rem; }
.clinical-checks { list-style: none; padding: 0; margin: 0; }
.clinical-checks li { padding: .7rem 0; border-bottom: 1px solid rgba(30, 58, 47, .12); font-size: .94rem; line-height: 1.55; }
.clinical-checks label { display: flex; align-items: flex-start; gap: .8rem; cursor: pointer; }
.clinical-checks input { flex: 0 0 auto; width: 1.1rem; height: 1.1rem; margin: .18rem 0 0; accent-color: #234c3b; }
.clinical-checks input:focus-visible { outline: 2px solid #a1472b; outline-offset: 3px; }
.clinical-checks label:has(input:checked) span { color: #506052; }
@media print {
 .eligibility-checklist { margin: 12pt 0; padding-top: 8pt; }
 .clinical-checks li { display: flex; gap: 6pt; font-size: 9pt; padding: 4pt 0; break-inside: avoid; }
 .print-checkbox { flex: 0 0 auto; }
}

/* Clinical protocol access */
.header-lock{margin-left:auto;flex-shrink:0;background:transparent;border:1px solid #a9b6a2;padding:8px 12px;min-height:40px;color:var(--ink);font-size:11px;line-height:1.4}.header-lock:hover{background:var(--soft);border-color:var(--ink)}
.access-view{display:grid;grid-template-columns:minmax(0,1.3fr) minmax(240px,.7fr);gap:70px;max-width:1120px;margin:0 auto;padding:85px 4.2% 100px;min-height:66vh;align-items:center}.access-card{max-width:530px}.access-card h1{font:400 clamp(42px,5.5vw,66px)/1.1 var(--serif);letter-spacing:-.04em;color:var(--ink);margin:0 0 24px}.access-intro{font-size:16px;line-height:1.75;max-width:40ch;color:var(--muted);margin-bottom:30px}.access-form{display:grid;grid-template-columns:minmax(130px,190px) auto;gap:10px 14px;align-items:start;max-width:440px}.access-form label{grid-column:1/-1;font-size:12px;font-weight:600;color:var(--ink)}.access-form input{min-width:0;width:100%;height:52px;border:1px solid #9aaa92;padding:12px 15px;background:var(--paper);font:24px/1.2 var(--sans);letter-spacing:.3em;color:var(--ink)}.access-form .solid-button{min-height:52px;padding:12px 19px;font-size:13px;white-space:nowrap}.access-form .solid-button:disabled{opacity:.65}.access-message{grid-column:1/-1;font-size:13px;line-height:1.7;color:var(--oxide);margin:4px 0 0;overflow-wrap:anywhere}.access-back{display:inline-block;margin-top:31px;padding:5px 0;border-bottom:1px solid var(--line);font-size:12px;color:var(--ink)}.access-aside{border-left:1px solid var(--line);padding:12px 0 12px 45px;max-width:310px}.access-mark{display:block;color:var(--oxide);font:34px/1 var(--serif);margin-bottom:25px}.access-aside h2{font:30px/1.2 var(--serif);letter-spacing:-.02em;color:var(--ink);margin-bottom:14px}.access-aside p{font-size:13px;line-height:1.8;color:var(--muted);margin-bottom:20px}.access-aside a{display:inline-block;font-size:12px;border-bottom:1px solid var(--line);padding-bottom:4px;color:var(--ink)}
@media(max-width:800px){.access-view{gap:40px;padding:58px 5% 70px}.access-card h1{font-size:44px}.access-aside{padding-left:25px}.header-lock{font-size:10px;padding:8px 10px}}
@media(max-width:600px){.access-view{display:block;padding-top:43px;min-height:65vh}.access-card h1{font-size:42px}.access-intro{font-size:15px}.access-form{grid-template-columns:minmax(115px,1fr) auto;max-width:100%}.access-aside{border-left:0;border-top:1px solid var(--line);padding:27px 0 0;margin-top:43px;max-width:none}.access-mark{display:none}.access-aside h2{font-size:26px}.access-aside p{margin-bottom:12px}.header-lock{margin-left:auto}}
@media print{#access-view,.header-lock{display:none!important}}

.protocol-lock-message{margin:0;padding:12px 4.2%;border-bottom:1px solid #d9bdab;background:var(--oxide-soft);color:#763a27;font-size:12px;line-height:1.7}.header-lock:disabled{opacity:.6}@media print{.protocol-lock-message{display:none!important}}

.note-intro{font-size:14px;line-height:1.75;color:var(--muted);max-width:58ch}.note-actions{display:flex;align-items:center;flex-wrap:wrap;gap:12px;margin:18px 0}.note-copy-status{font-size:12px;color:var(--ink);line-height:1.6}.note-template-label{display:block;font-size:12px;font-weight:600;line-height:1.6}.note-template{display:block;box-sizing:border-box;width:100%;max-width:100%;margin-top:9px;padding:20px;border:1px solid var(--line);border-radius:0;background:#fafaf5;color:var(--ink);font:13px/1.8 ui-monospace,SFMono-Regular,Consolas,monospace;resize:vertical;white-space:pre-wrap;overflow-wrap:anywhere}.note-template:focus-visible{outline:2px solid var(--oxide);outline-offset:3px}.procedure-note-print{white-space:pre-wrap;overflow-wrap:anywhere;font:10pt/1.6 Arial,sans-serif}.figure-legend{margin:12px 0;padding:12px 15px;border-left:2px solid var(--sage,#829779);background:var(--soft);font-size:12px;line-height:1.7}.figure-legend dt{font-weight:650}.figure-legend dd{margin:0 0 5px}.figure-legend dd:last-child{margin-bottom:0}@media(max-width:600px){.note-template{padding:14px;font-size:12px;min-height:28rem}.note-copy-status{max-width:34ch}}@media print{.note-actions,.note-intro{display:none!important}.note-template{height:auto;border:0;padding:0}}